Ongoing Research


Sickle Cell Surveillance at Sickle Cell Anemia Diagnosis Priority Sites of NPHL


Sickle cell disease is a group of disorders typically inherited from parents that affects the hemoglobin molecule inside red blood cells. It is one of the most common hemoglobinopathy affecting 20 – 25 million populations globally. Nepal lies in the southern part of Asia where most of the indigenous group of people are living. A study from Nepal reported high burden of sickle cell disease among indigenous Tharu population. There are very limited study regarding the burden of sickle cell diseases among Tharu and other communities in Nepal. Nepal government has started diagnostic services for the diagnosis of sickle cell disease from the past few years but has not been able to implement a strong plan to control this inheritable disease in absence of generalized data of the affected group and communities. In this regard we targeted to find the status of sickle cell disease among different communities using secondary data from all over Nepal.

The study will be carried out for the period of three months and financial support will be provided by National Public Health Laboratory. Secondary data will be collected from the testing site, under National Public Health Laboratory to meet objective of the study.

The collected data will be entered and analyzed using Statistical Package for Social Sciences (SPSS). The final report will be communicated to Ministry of Health and Populations.


Administrative Information

Principal Investigator:             Dr. Rekha Manandhar Shrestha, M.D

                                                Senior Consultant Pathologist, NPHL


Co-investigators:                  Roshan Pandit

                                                Bachelor of Science in Medical Lab Technology

                                                Medical Lab Technologist, NPHL


                                                Rameshwar Das

                                                Bachelor of Science in Medical Lab Technology

                                                Medical Lab Technician, NPHL


                                               Udaya Kumar Yadav

                                               Bachelor in Medical Lab Technology

                                               Medical Lab Technologist, NPHL



Supervisors:                           Asso. Prof. Dr. Binod Kumar Yadav

                                                 Ph.D. (Biochemistry and Genetics)

                                                 Postdoc (Molecular Biology and Neuroscience)

                                                 Head, Dept. of Biochemistry, IOM, TUTH


                                                 Prof. Dr. Harish Chandra Upreti,  M. Phil. (Pathology)

                                                 Director, NPHL